IMM250H1 Lecture Notes - Lecture 6: World Health Organization, Smallpox Vaccine, Ebola Vaccine
Document Summary
Edward jenner"s legacy & the eradication of smallpox. 1700s smallpox is a dreaded disease; often kills of the population wherever there is an outbreak. 1796 jenner performs the first smallpox vaccination. 1800s smallpox vaccination spreads throughout the developed world. However, smallpox was still endemic in many parts of the world. The world health organization (who) & eradication campaign (1967-1976) Ring vaccination when time/resources are limited; vaccinate only those most likely to be infected (contacts & contacts of contacts) By 1980, smallpox is eradicated from earth. ** vaccination is considered one of the greatest public health achievements of all time ** 1988 estimated 350,000 cases, mainly in developing countries; 1/200 infections leads to permanent paralysis & 5-10% of those cases leads to death (breathing muscle paralysis) Virus doesn"t survive long in the environment & doesn"t infect other species (ie. no reservoir) Two safe and effective vaccines salk vaccine (killed virus) & sabin vaccine (attenuated virus)
