IMM350H1 Lecture Notes - Lecture 5: Alternative Splicing, Bcl10, Subtyping

Define pleiotropy, redundancy, synergy, antagonism, and cascade induction as they apply to cytokine action. Give examples of each. *only need help only with some good examples* Pleiotropy —one cytokine produces multiple effects Redundancy—more than one cytokine induces the same effect Synergy—two (or more) cytokines work together to induce an effect Antagonism —one cytokine can inactivate the effect of another Cascade induction – one cytokine’s action on a target cell induces the cell to produce one or more additional cytokines