IMM250H1 Lecture Notes - Lecture 3: Tlr5, Ruslan Medzhitov, Commensalism
Document Summary
Imm250 lecture 3 : shigella"s portal of entry - the m cell, m cells kind of epithelial cells overlies the peyer"s patches which is between villi. Innate immune detection (this lecture: cellular and humoral innate factors (next week) Innate immunity: innate denotes a property of some thing or action which is essential and specific to that thing or action, and which is wholly independent of any other object, action or consequence. Represents the immune system is in most multicellular organisms (from plants, sea urchins, flies, hydra, etc) - innate immunity is in both multi cellular organisms. Most of the time this is the efficient system against microorganisms, Innate and adaptive immunity work together in humans l in the absence of innate immunity, infections cannot be controlled. Need innate immunity to initiate adaptive immunity. l in the absence of adaptive immunity, infection are first controlled by innate immunity but cannot be cleared.