IMM250H1 Lecture Notes - Lecture 5: Tumor Antigen, Adaptive Immune System, Humoral Immunity
Document Summary
Imm250 lecture 5: growing an adaptive immune system. Immune system must recognize and respond to internal threats. Feb. 14, 2018: lymphocytes mediate adaptive responses by recognizing unique, complex structures called antigens, antigens, other types of antigens, p(cid:396)otei(cid:374) a(cid:374)tige(cid:374)s: (cid:862)self(cid:863) a(cid:374)tige(cid:374), (cid:862)tu(cid:373)ou(cid:396)(cid:863) a(cid:374)tige(cid:374), t(cid:396)a(cid:374)spla(cid:374)ted tissue, (cid:862)(cid:374)eo(cid:863) a(cid:374)tige(cid:374), alle(cid:396)ge(cid:374) Feb. 14, 2018: the cellular vs humoral immune response involves recognition of different kinds of antigens, lymphocytes form the adaptive arm of the immune system, b cells and t cell antigen receptors: Feb. 14, 2018: b cells have antibody molecules, t cells have t cell receptors, the cellular vs humoral immune response involves recognition of different kinds of antigens. Feb. 14, 2018: antigen presenting cells may be virally infecte. Ho(cid:449) the adapti(cid:448)e (cid:396)espo(cid:374)se (cid:272)a(cid:374) (cid:858)see a(cid:374)(cid:455)thi(cid:374)g(cid:859) (diversity: one antigen specificity per lymphocyte, bcrs (or tcrs) on a given b or t lymphocyte are: Identical: expressed as hundreds of thousands of copies, unique to that lymphocyte, highly specific for a particular antigen.
