Lecture 27 Pharmacoeconomics
Douglas pushed for socialized medicine; believed it was unethical to profit from sickness.
Canada Health Act
Principles: comprehensiveness, universality, portability, accessibility.
Covered: hospital, physician, emergency diagnostics, inpatient medications.
Not covered: outpatient medications, most allied health, densitry, non-medically necessary
Health expenditure per capita varies widely across countries.
US spends the most.
Increasing costs of healthcare.
Healthcare spending: mostly on hospitals. Drugs that do not require hospitalization save
health care system.
Government themes: Fiscal Restraint
•Increased regulation of new technology, assessment of economic impact, cost-
effectiveness, cost-utility, trade-offs.
Increased Drug/Technology Expenditures
•More expensive products
•More prescriptions/utilization for more patients
Finite funding envelope: limited money available, depends on taxes
Metastatic colon cancer
•Leading cause of cancer
•Tumor in colon, rectum, appendix
•Colorectal cancers arise from polyps in colon
•Commonly spreads to liver
•Drug class; EGFR inhibitor
•+2 months survival
•1% population affected; auto-immune disease affects joints, skin, organs,
•Treatment: disease modifying antirheumatic drug and anti-inflammatory agents,