PCL475Y1 Lecture Notes - Lecture 7: Substantia Gelatinosa Of Rolando, Posterior Grey Column, Raphe Nuclei
28 Aug 2019
School
Department
Course
Professor
Document Summary
Lecture 7: melzack"s gate theory & analgesics-nsaids (pain 3) Influential canadian psychologist in mcgill (expert on pain: originator (with wall) of gate control theory. Melzack"s model: 2 aspects of the theory, no-specificity (not widely accepted, gating of pain (widely accepted) Non-specificity: there are no special pain receptors or pathways, pain is a perception by cns, perception that there is too much activity in any sensory system. Gct: mark ii: biggest box represents the dorsal horn of spinal cord. Into it, l (a and b) and s (delta and c) fibers. In the dorsal horn, there is substantia gelatinosa (lamina 1,2) Has cell bodies in sg that project to t cells (second order cells) Large ones fire with light pressure, small ones fire with stronger pressure: goes up to brain (action system), producing behavior. L fibers associated with inhibitory neurons in sg elimination. S fibers associated with excitatory neurons in sg more excitation.
