PCL102H1 Lecture Notes - Lecture 19: Neglected Tropical Diseases, Zika Virus, Miskito People

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This pro(cid:272)ess takes (cid:1005)(cid:1006)-15 years and it costs 1-2 billion $. Nigeria is considered ground 0 to neglected tropical diseases. Asia has the most new cases of neglected diseases, and this is because of rapid economic growth and this creates pockets of poverty. There is an overlap with where these neglected tropical diseases are found. This disease is caused by a worm and its spread by misquitos. When the misquito bites the human, it injects the human with a larvae. The worm then grows in the lymph nodes. Light shade is number of zika viruses, and the dark graph is the neurological disease. 1% of clinical trials are for neglected diseases. Therapeutic index is how safe a drug is. Warfarin has a low index because if you give too much they will bleed. Vitamin c has a high index because its safe. Off la(cid:271)el drugs are drugs (cid:449)hose indi(cid:272)ation (cid:449)asn"t set out to treat a spe(cid:272)ifi(cid:272) disease.

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