Biochemistry 2280A Lecture Notes - Lecture 21: Glycogen, Cholesterol, Ketone Bodies

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Chris Brandl

Document Summary

Biochem lecture 21 energy metabolism: the big picture. Topic 17 learning objectives energy metabolism energy indicators such as atp, amp, nadh and acetyl-coa. Explain the effects of insulin and glucagon on the main pathways of. Explain the metabolic implications of high or low levels of key cellular. Describe the metabolic responses to prolonged fasting. Describe the molecule basis and metabolic consequences of diabetes mellitus. Blood glucose is high, pancreas secretes insulin. Eventually, [atp] and other energy indicators increase, inhibiting. Glycogen synthesis, fatty acid synthesis, pentose phosphate pathway, Unfed state amino acids from protein degradation) produces ketone. Blood glucose is low, pancreas secretes glucagon. Glucose is produced from glycogen and then gluconeogensis (produced. Adipocytes release fatty acids from storage, and eventually, liver. Biosynthesis is not favoured (fatty acids from stored triacylglycerol) Muscles pick up whatever it can, brain is peculiar and it won"t pick up. Adipocytes break down triglyc to fatty acids fatty acids.