Biochemistry 2280A Lecture Notes - Lecture 22: Cortisol, Histone Deacetylase, Rna Splicing

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3 main topics: gene expression, recombinant dna technology, molecular basis of cancer. Objectives: increase your ability to obtain and use biochemical information provided in different formats, understand mechanisms of information flow in the cell. This relates to gene expression lectures: think critically about why biochemical mechanisms occur as they do. Why things work that way: consider how structure relates to function. Why do things happen that way: introduce you to a few concepts of experimental. Design: describes how biochemistry relates to diseases. Read textbook & note summaries before coming to class. The human genome encodes a total of about 21,000 different proteins in the genome. In any cell type, less than 10,000 are expressed. The expression of genes will differ between different organs by accumulation of different sets of rna and proteins. Proteins expressed in the brain vs the liver are different (some expressed in liver and some not expressed in brain).

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