Biochemistry 2280A Lecture Notes - Lecture 19: Histone H3, Histone H4, Histone H1

20 views4 pages

Document Summary

Explain the different levels of structural organization displayed by dna in eukaryotic cells. Explain the effect of dna packaging on gene expression and identify, in general terms, the key mechanisms cells use to alter dna packaging to regulate gene expression. The human genome is about 3 x 109 base pairs long. At 0. 34 nm per base pair, that"s 102 cm. Human dna must be condensed about 10,000-fold to fit inside the nucleus. Despite being condensed, dna must remain available for replication, repair and gene transcription. Eukaryotic dna is condensed with the help of specialized proteins. Eukaryotic proteins involved in condensing dna (bacteria use different proteins) Five types: h1, h2a, h2b, h3, and h4. Contain fewer than 200 amino acids (very small) Rich in lysine and arginine residues: much larger abundance compared to normal amount o o o. These molecules are involved in packaging dna (have to associate with dna)

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions