Biology 2581B Lecture Notes - Lecture 4: Transcriptome, Central Dogma Of Molecular Biology, Genome Size
24 Feb 2014
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Advantages: ease of storage (large quantity of data, can be copied reliably. Analogous to storing electronic data such as music: digitized information on your computer hard drive (cid:240) mp3 player (cid:240) sound waves (cid:240) music. The central dogma is generally not true, as there are rnas that are not transformed into proteins but stays true for the most part. The flow of information in biological systems: read in two orders, one strand is 5" to 3" directionality, complementary strand is 5" to 3" in the direction. A specific segment of dna at a specific location in the genome (on a region of a chromosome) that serves as a unit of function encodes rna or protein codon is found translation out, Basic transcriptional machinery gc, caat, tata box. 5" utr (untranslated region) not translated, where transcription starts: rna polymerase starts building nucleotides here, within exon 1 (or exon 2 or 3), the start. Proteins stop at 3" utr but rna continues.
