Biology 2581B Lecture Notes - Lecture 21: P Element, Gynandromorphism, Zygote

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21 - transposable elements and variations in chromosome numbers. But rst evidence by marcus roades in 1930s. Described in detail and con rmed by barbara mcclintock later on: transposable elements are jumping genes. Exist in many almost all organisms with many different types (ex: mammals, insects, plants) Can be 50bp - 10kb (10 000bp) in length. Different copy numbers: can be present in a genome anywhere from 1-100 thousands times. Transposable elements are similar to retrovirus possibly indicates that viruses evolved from retrotransposons. However, there are exceptions where they have functions in the host maintain telomere length in drosophila (requires. Sel sh = carrying only information that allows their self-perpetuation (insert & jump within host genome independently) speci c te in their bodies, have to be modi ed in order to be active: transposable elements in the human genome. Have an impact on: genome evolution, genome size & structure, gene expression depending on the site of insertion, statistics.

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