Microbiology and Immunology 3300B Lecture Notes - Lecture 8: Complement Receptor 1, Decay-Accelerating Factor, C5-Convertase
3 Mar 2018
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Document Summary
Focus on innate immunity so far with prr & pamp/damps. Now more focus on adaptive immunity this lecture bridges innate to adaptive as these two cannot be separated. Compare and contrast of innate vs adaptive immunity; Receptors involved in innate are germ-line encoded do not vary from somatic to another somatic. Adaptive every person and every cell is different due to recombination. Innate no specificity: lps is recognized by innate but structure is similar among many species among bacteria (what it means by no specificity, adaptive on the other hand can distinguish at molecular level. Innate has no memory but some type of epigenetic memory involved but adaptive has specific surviving clone of cells that expresses specific receptors for past antigens. Innate present from birth but adaptive formed as it is encountered (diff b/w newborn vs 8 year olds: mothe(cid:396)"s adaptive immunity (iga) passed to the baby primarily by breastfeeding and not inherited b/c through feeding.
