Pathology 3240A Lecture Notes - Lecture 8: Deep Vein Thrombosis, Oncotic Pressure, Blood Pressure
29 Sep 2017
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In chapter 3: hemodynamic disorders, thromboembolism and shock pp. Survival of cells and tissues is dependent on the oxygen provided in the blood supply as well as on a normal fluid balance. 60% of the person"s body weight is water. Definition: accumulation of abnormal fluids in the interstitial / intercellular tissue (cid:314) swelling of the subcutaneous tissues. Local factors lymphatic obstruction: vascular permeability. Systemic factors: cardiovascular function, overall fluid balance, salt retention. Starling"s law: movement of fluid between vessels and tissue governed by balance between 4 forces: (see. Hydrostatic pressure in vessel which measures: 32 mmhg at arterial end, 12 mmhg at the venous end. Oncotic pressure = colloid osmotic pressure (cop) of plasma (26 mmhg) which reflects the amount of serum protein (albumin). Disturbed blood flow & hemodynamics the flow of. Intravascular hydrostatic pressure and interstitial fluid osmotic pressure tend to move fluid outward. Conversely, interstitial fluid pressure and plasma osmotic pressure draw fluid inward.
