Pathology 3240A Lecture Notes - Lecture 2: Avascular Necrosis, Red Blood Cell, Mutation

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If you understand the cause, you can either prevent it or treat it early. Idiopathic don"t know what the cause is; but this area is getting smaller and smaller with advances and more and more knowledge of disease, etc. Probably very two strong influences on the runner"s death. There are diseases that are purely genetic (sickle cell disease) There are diseases that are purely environmental (traumatic head injury, no relevance to who your parents are) And there are diseases of both: heart disease, diabetes, cancer (a lot of these require a predisposition and also external influence, although not everyone with the disease is involved with one or the other) Native population and south east asia diabetes. Wide range: single mutation in a dna base pair gain/loss of whole chromosomes. Far more common to be a sporadic mutation acquired through life. Pulmonary hypertension: areas of low oxygen that eventually infarcts, may have some protective value against malaria.

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