Pathology 3500 Lecture 30: Lecture 30
28 Mar 2018
School
Department
Course
Professor
Document Summary
Stimulate rbc production (epo: the kidney filters the blood, regulates a lot in the body, maintains homeostasis. Kidney gross anatomy: outer is the cortex where most filtration happens, middle is where concentration of urine is, reclaiming of things happens in the middle (ex. Reclaiming of water: renal pelvis is the collecting pouch of the urine. Lined by endothelial cell and have protein mesh called glomerular basement membrane: have supporting cells on the out side which make slits. Endothelial fenestrations: the blood vessels have holes in them allowing fluid to pass more easily. It is also neg charged so acts as a charge barrier. Loop of henly is where the concentration happens then it goes to distal tube for additional processing. Causes of acute kidney failure (can be acute, sudden onset or chronic: pre-renal / systemic - things that go wrong before blood hits the kidney, shock, dehydration, hemorrhage, anaphylaxis, renal.
