Pathology 3500 Lecture 2: Week 2
Document Summary
Broadly speaking, what is disease grounded in: disease is grounded in injury sustained to individual cells. Lysosomes break down proteins and other molecules and recycle them potential, which requires energy. Ion flux, maintaining gradients and transport, as well as the receptors: the cytoskeleton must maintain its integrity. What four components/functions of the cell are particularly vulnerable to damage: cell membrane, critical for ionic and osmotic homeostasis, mitochondria, generation of energy via atp, protein synthesis, dna. It is a pattern of response of living organisms to injury. It results when the cell cannot adapt, if the adaptive mechanism fails, or if the adaptive mechanism itself becomes harmful. Irreversible damage and cell death: the moment when reversible damage become irreversible cannot be well defined. What is the cell"s response to sublethal long-term or chronic stimuli: the cell has to adapt to the environment and achieve a new steady state that preserves its.
