Pharmacology 3620 Lecture Notes - Lecture 7: Sympathomimetic Drug, Low-Density Lipoprotein, Adipose Tissue

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Distribuion of adults by bmi and age group canada 2009-2011. Trend shows an increase in obesity of males and females in all age groups. In some age categories, the rates are very high (40-59 and 60 to 79) Increased health risks for a bmi of 25 or higher. Bmi is a tool but doesn"t correlate body type/weight to health status per say. Does not relect body mass and body types based on ethnicity. Issue is in children: 12-17 years old in the male category more than 40% are obese. More lipids coming out of the liver ectopic lipid deposiion. Muscles that don"t respond to insulin anymore. Vascular disease hypertension (deposiion of lipid in muliple issues (steatosis) Pharmacological treatment of metabolic syndrome muliple drugs required for complex diseases. Metabolic syndrome: obesity + at least 2 of the following: i) ii) iii) iv) v) vi) Vascular disease / pre-diabetes or type 2 dm.

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