Physiology 1021 Lecture Notes - Lecture 3: Common Hepatic Duct, Portal Vein, Bile Canaliculus

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Connected to the upper portion of small intestine via 2 ducts where pancreatic juices come into contact with chyme. Exocrine secretions come from a few different cells found within the epithelial clusters found in the pancreas. 2 ducts connect pancreas to duodenum- ducts collects the exocrine secretion. Duct cells also make exocrine secretions, like bicarbonate and water. Hcl that"s there, need to neutralize it: pancreatic amylase- Tripsinogen is inactive enzyme, needs to be cleaved into active form of trypsin. Procolipase is inactive protein (not an enzyme) trypsin cuts it into colipase. Prophospholipase inactive, trypsin cuts it into phospholipase- breaks down phospholipids. Decreases glucose in blood by moving glucose into cells. Skeletal muscle and fat (adipose) cells, insulin release enhanced by glucose insulinotrophic peptide (gip: glucagon . Increases glucose in blood, releasing from cell stores. Decreases digestive activity by decreasing acid production in the stomach. Main cell type of liver are hepatocytes.

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