BI110 Lecture Notes - Lecture 26: Cellular Respiration, Acetyl Group, Flavin Mononucleotide

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8 Dec 2016
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Electrons removed in oxidation: accepted by nad+ or fad. Each acetyl group oxidized produces: 2 co2, 1 atp, 3 nadh, 1 fadh2. 8 steps in the cycle, each with its own enzyme to catalyze the reaction. For every acetyl-coa molecule, 2 co2, 3 nadh, 1 fadh2, and 1 gtp are released. Electrons passed from nadh and fadh2 to o2. Electron transport chain includes: 4 membrane protein complexes (inner mitochondrial membrane, 2 smaller mobile electron carriers ubiquinone (uq) and cytochrome c (cyt c). Energy released used to pump protons across inner mitochondrial membrane. 3 major protein complexes (i, iii, and iv: pump h, contain prosthetic groups redox active cofactors, cycle between reduced and oxidized states, the proteins themselves are not undergoing redox reactions. Electrons: depleted of energy, delivered to oxygen as final electron acceptor. Steps of the electron transport chain: nadh delivers electrons to nadh dehydrogenase (complex i). Electron flow is downhill: each carrier is more electronegative than the last.

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