BI110 Lecture Notes - Lecture 5: Electronegativity, Covalent Bond, Liposome

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29 Apr 2016
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Water molecules are polar (unevenly distribution of charge within the molecule) Electronegative oxygen atom associates with electropositive hydrogen atoms of adjacent water molecules to form hydrogen bonds. Hydrogen bonds are also important in dna and proteins. Typical hydrogen bond is like 1/10 the strength of a covalent bond. Solvent is a fluid in which a solvent can be dissolved (water is solvent, kool aid powder is solute) Polar/charged molecules form hydrogen bonds or ionic bonds with water molecules. Hydrophilic ( water-loving ): sugars, dna, rna, organic acids and some amino acids water is the solvent in cells(aqueous solutions) Hydrophobic( water-fearing ): do not dissolve in water, lipids (hydrocarbons) and some amino acids. Disrupt hydrogen bonded structure of water (adding oil to water) Water molecules tend to exclude molecules that disrupt hydrogen bonding. Hydrophobic interactions are a major driving force in folding of molecules (like proteins), assembly of cellular structures, and membrane organization. Polar head(hydrophilic) and 2 non-polar hydrocarbon tails (hydrophobic)

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