BIOL 1000 Lecture Notes - Lecture 26: Elongation Factor, Alternative Splicing, Transfer Rna
Document Summary
Translation - elongation: the amino acids in the p site get transferred to the trna on the a site, and the one in the p site gets pushed to the e site and leaves. Peptide elongation during translation: bringing in the trna into the a site and making it match the codon doesn"t just happen on its own. It requires an elongation factor, which uses gtp for energy. Its the hydrolysis of the gtp that pushes the ribosome along, and pushes the trna into the next site. Lots of ribosomes can associate with the mrna at the same time to form lots of polypeptides at the same time. After proteins get translated, they are not usually functional. They still have to be modi ed by having amino acids removed from them or sugars added to them. Determining how much of a functional protein is available in a cell at any time is referred to as regulation.