BIOL 1001 Lecture Notes - Lecture 37: Hox Gene, Gene Duplication, Stoma
Document Summary
A gene is free from prior selection pressures. Possilble outcomes of gene duplication: duplicated genes retain original function-> provides additional quantities od same product, may retain original function, but change in expression patter. Big morphological changes are possible through changes in when/where a gene is expressed. Hox genes control head to tail organization in body. Humans have 4 sets of hox genes; flies have 1 set of hox genes. Differentiation results in different cells due to different genes that are turn on/off due to different transcription factors. Embroyonic stem are cells that become any type of stem cells. The hox genes are turned on in the order they are found in the chromosomes. They match up where they are found in the body. The hox genes are on at different times and how long they are on. Mutations in genes controlling development can have profound effects on morphology. Hetrochrony-> changes in timing of development events b/t 2 taxa.