BIOL 2021 Lecture Notes - Lecture 92: Acetyl-Coa, Citric Acid Cycle, Isocitric Acid
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Aerobic respiration: the krebs cycle (cid:170)(cid:3)review: during glycolysis, one molecule of glucose is split to form two pyruvate molecules, with a net profit of two atp. Step 1: in the first step of the krebs cycle, acetyl coa is added to oxaloacetate to form citrate. Note that coenzyme a (coa-sh) is removed in the process. Step 2: citrate is isomerized forming isocitrate, which is less stable than citrate. During this step, one water molecule is removed and another water molecule is added. Step 3: isocitrate is converted into alpha- ketoglutarate. In this process, isocitrate is decarboxylated (carbon dioxide is removed), and nad+ is reduced, forming nadh + h+. www. thinkwell. com info@thinkwell. com. Step 4: alpha-ketoglutarate is converted to succinyl coa. During this step coenzyme a is added, carbon dioxide is lost, and nad+ is reduced, forming. Step 5: succinyl coa is converted to succinate. During this step fad is reduced forming fadh2.
