BIOL 2021 Lecture 11: lipid composition

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Lipid composition is different in different organisms and organelles because membranes vary in function. In archaea, lipids usually contain prenyl chains instead of fatty acids. Plasma membranes of most eukaryotic cells are more varied than prokaryotes and archaea: large amounts of cholesterol, contains a mixture of different phospholipids. E. coli has no cholesterol: few phospholipids, no glycolipids. Plasma membrane: has lots of cholesterol, sphingolipids, and ptd cho. Mitochondria: has little cholesterol and no sphingolipids. Inositol phospholipids are present in small quantities in animal cell membranes and have a role in cell signaling and cell traffic. Different kinds of lipids are usually only found on one side of the membrane. Ptd ser on the inside which creates a negatively charged environment on the inner leaflet. Cholesterol is evenly divided between the 2 leaflets because it can easily flip flop between the 2 bilayers.

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