BIOL 104 Lecture Notes - Lecture 3: Vascular Endothelial Growth Factor, Blood Vessel, Oncogene

57 views2 pages
24 Apr 2018
School
Department
Course
Professor

Document Summary

Cancer statistics: of all men will develop cancer cause of 1/3 of all women will develop cancer, 2nd leading death in the us (heart disease is #1, 5-year survival rate is 68% Tumors turn on genes that attract blood vessel growth: example: vascular endothelial growth factor (vegf, early diagnosis increases survival. A history lesson : the first cancer links to specific substances. At the beginning of the 20th century they knew : specific environmental factors (mutagens) can induce cancer (carcinogens, some cancers are heritable (5-10%) (smoking makes you 23x more likely to develop lung cancer) There are two types of cancer-related genes: oncogenes, tumor suppressor genes, proto-oncogenes stimulate normal cell division, pro-oncogene growth protein mitosis and cell survival. How can a proto-oncogene to become and oncogene: mutations in the gene can cause the protein to be hyperactive, translocations can put a gene next to a promoter that is always on.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions