BIOL 3327 Lecture Notes - Lecture 25: Phagocytosis, Apoptosis, Ctla-4

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Cd59: 3rd powerpoint humoral immunity, when daf and cd59 complement cytokines are missing, one will develop. Pnh causes red cell lysis, loss of iron and blood clots: both daf and cd59 are inhibitors of the complement system, and when they are missing, the complement system can go haywire and damage nearby cells. Cd69: 2nd powerpoint cytokines, the second step of t cell activation (retention in lymph node) cd69 is expressed on the lymphocyte surface. Cytochrome c: 5th powerpoint autoimmunity, after bh3 attaches to the mitochondria, the mitochondria leaks cytochrome c, which activates capsase-9 causes dna fragmentation and death. Daf: 3rd powerpoint humoral immunity, stands for decay accelerating factor, this is an inhibitor of the complement system, and when it is missing alongside. E-selectin: 4th powerpoint immunity at epithelial barriers, e-selectin grabs the cla ligand on t cells and pulls it into the skin.

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