BSC 444 Lecture Notes - Lecture 7: Guanosine Triphosphate, Tata Box, Rna Virus

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Tata box, hepatitis b virus has 4 promoters and only 1 of them has a tata box) Transcription factors: bind specifically to promoter and enhancer sequences to control gene expression, some viruses produce their own, some cellular transcription factors can activate or repress transcription of viral genes. Is a complex of 13 proteins: binds to the tata box, one of those 13 proteins is the tata box binding protein, after tfiid binds the tata box, other general transcription factors and rna polymerase bind. Transcriptases: general term for an enzyme that carries out transcription (aka rna polymerase, viruses that replicate in the nucleus usually use a cellular transcriptase, viruses that replicate in the cytoplasm encode their own transcriptase. Rna virus transcriptases: rna virus need an rna-dependent rna polymerase (rdrp) to transcribe their genes, viruses in classes iii, iv and v encode their own transcriptases.

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