KINE 200 Lecture Notes - Lecture 9: R.W.D. Molenbeek, Antigen, Zygosity
2 Mar 2017
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Document Summary
The case where a heterozygous does not look like the homozygous dominant individual. Disease of the blood cells - usually lethal by the time a person reaches their twenties: african americans, caucasians of mediterranean descent. Causes the cells to form a sickle like shape leads to reduced oxygen flow to vital organs. Carrier state not diseased but do have some sickling of the cells - protective against malaria. 1 in 22 african american born in the states. For some traits, we have multiple alleles that can influence the phenotype. Unlike mendelian, where the traits all have two alleles. Blood typing is the most common example as there are three alleles that play a role. The i gene has 3 alleles - a, b or o. Although there are three alleles, each human only has two or the three. Codominant two dominant genes are present and both are fully expressed a & b are both dominant - leading to type ab.
