ANTH 350 Lecture 8: Plasma Proteins
Document Summary
Plasma proteins: plasma proteins: apolioproteins, beta liptoproetins and beta glycoproteins. Associated with lipid metabolism and components of low density (ldl) high density (hdl) and very low density (vldl) lipoproteins. Arterosclerosism , coronary artery disease, alzheimer"s: apoliprotein e. Plasma lipid levels, lipd transport in tissues, cholesterol absorption of intestines. Three common alleles apoe*2, apoe*3 and apoe*4. Ancestor condition seems to be apoe 4. = correlation with e4 allele suggest it is related to climate and food systems. Hunter gatherer- more e4 agriculture = e3: =e4may be a thrifty allele---allows to store more fat. Because when hunter/gatherer will go through food cycles. E4 people more susceptible to coronary artery disease, alzheimer"s when exposed to western diets. = selected against (e4: humans and their commensals. Other species receive benefits from following humans around. Studying species that follow us might tell us something about human evolutionary history and migration. Pacific rats- history of human settlement in pacific.
