ANSC 1210 Lecture 11: Lecture 11

12 views4 pages

burgundygnat179

19 Nov 2021

School

University of Guelph

Department

Animal Science

Course

ANSC 1210

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Stress response: evolved to handle physical threats such as temp. changes or the appearance of a predator, psychological threats elicit a similar response, coping mechanisms/adaptive changes. Activation of the sympathetic nervous system and adrenal medulla. Its known as the visceral or involuntary nervous system: the ans functions w/out conscious, voluntary control, innervating: And various endocrine and exocrine glands: the ans influences activity of most tissues and organ systems in body, therefore, the ans makes significant contribution to homeostasis. Physiology of ans: sympathetic system controls fight or flight responses, parasympathetic system regulates rest and digest functions. Measurement of ans: ans response = acute measure, pathological changes = chronic measure, direct: heart rate variability, blood pressure, body temperature, respiratory rate, catecholamine levels. Physiological stress response: measurement techniques: arguments for and against. Measure of chronic welfare change: blood pressure example. Change in welfare = change in blood pressure (bp) Daily exposure to noise, flashing light = bp rise: body temperature.

Related Questions

What are prions?

In cell, there are subcellular organelles. They are not full organism. Prions are just proteins. They don't have any other macromolecules. Prions have capacity to form copies through replication. They replicate through free radical and chain mechanism.

Doctor Stainly pruisne work on prions and show it's relation with disease called mad cow disease. ( This is neurodegenerative disease and responsible for harmful effects on brain).

In Australia sheep was infected with prions, caused scarpie disease in sheep. Organs of sloghed sheep were used in cow feedd. When cow consume feed, prions were transmitted to cow and cow start to show unusual behavior.

Symptoms of prions infection are like that of some disease

Kurulyprosy
Insomnia
Dimensia

Detection of prions: Prions can be detected by Western bloting.

Normal prions:

Normal prions are present in our body. They don't have tendency to form rigid aggregate. They are quite less in number. They have following functions

Cellular differentiation
Store elemental surplus that is used in future
Memory enhancement

Molecular basis of prions:There is some difference in structure of Normal and abnormal prions.

Normal prions have molecular weight 33-35KD while abnormal prions have molecular weight 27-30KD
In normal prions at position 178 amino acid aspartate is present while in abnormal prions at 178 position asparagine is present.

Prions diagnosis and analysis:

Brain biopsy....in past for taking sample brain biopsy was used but now a days tonsils biopsy is used for sampling.

Immuno fluorescence:Biopsy sample is taken on slide and it is treated with antibody ( of abnormal prions) which is against normal prions. Speciality of antibody is that when it bind with abnormal prion it will glow. If we capture fluroscene it's mean abnormal prion is present in sample. As abnormal prion antibody was label with fluroscene probe. So patient sample will show fluroscene while normal sample will not show fluroscene.

Transmission of prions: Normally prions can't Cross specie barrier they transmitted through different ways. Like as formite

If a person is effected with prions and he has wound in head and his comb is used by another person so prions can be transferred to other individual. Comb is Carrier of prion.

Prions are very slow acting immune system can't destroy them.

skyalpaca180

ANSC 1210 Lecture 11: Lecture 11

Document Summary

Get access

Related Documents

BIOL 1050 Lecture Notes - Lecture 28: Allostasis, Positive Form, Stressor

PSY100H1 Chapter Notes - Chapter 14.2: Psychoneuroimmunology, Type A And Type B Personality Theory, Pituitary Gland

BIOL 1050 Lecture Notes - Lecture 29: Parasympathetic Nervous System, Sympathetic Nervous System, Preganglionic Nerve Fibers

Related Questions