HSS 1100 Lecture Notes - Lecture 10: Hospital-Acquired Infection, Sepsis, Hand Washing

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josiepayne03

27 Jun 2022

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University of Ottawa

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Health Sciences

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HSS 1100

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Infection that wasn"t present at the time of admission. 25% of patients will pick up infection. Patients are already suspectable bc they"re immune system is likely weakened (which would be why they"re in the hospital) Bad handwashing, leaving stuff inside patient, coughing. Immunodeficient patients, surgeries where organs are seriously damaged, gunshot or stabbing to gi- tract. Any procedure that is microbial pathogens in immunocompromised patients. 3 key factors that play a role in the transmission of a nosocomial infection (all need to be present) Identify highest risk area in hospital: hospital will never be 100% sterile, what can we do? . Route of infection: education of staff, patients, visitors, proper procedures, handwashing, what can be done? . Identify patients at highest risk and protect them as much as possible: what should you do? . Important to how we approach the control of infections. Put into place in 80s to control aids in hospitals.

Related Questions

What are prions?

In cell, there are subcellular organelles. They are not full organism. Prions are just proteins. They don't have any other macromolecules. Prions have capacity to form copies through replication. They replicate through free radical and chain mechanism.

Doctor Stainly pruisne work on prions and show it's relation with disease called mad cow disease. ( This is neurodegenerative disease and responsible for harmful effects on brain).

In Australia sheep was infected with prions, caused scarpie disease in sheep. Organs of sloghed sheep were used in cow feedd. When cow consume feed, prions were transmitted to cow and cow start to show unusual behavior.

Symptoms of prions infection are like that of some disease

Kurulyprosy
Insomnia
Dimensia

Detection of prions: Prions can be detected by Western bloting.

Normal prions:

Normal prions are present in our body. They don't have tendency to form rigid aggregate. They are quite less in number. They have following functions

Cellular differentiation
Store elemental surplus that is used in future
Memory enhancement

Molecular basis of prions:There is some difference in structure of Normal and abnormal prions.

Normal prions have molecular weight 33-35KD while abnormal prions have molecular weight 27-30KD
In normal prions at position 178 amino acid aspartate is present while in abnormal prions at 178 position asparagine is present.

Prions diagnosis and analysis:

Brain biopsy....in past for taking sample brain biopsy was used but now a days tonsils biopsy is used for sampling.

Immuno fluorescence:Biopsy sample is taken on slide and it is treated with antibody ( of abnormal prions) which is against normal prions. Speciality of antibody is that when it bind with abnormal prion it will glow. If we capture fluroscene it's mean abnormal prion is present in sample. As abnormal prion antibody was label with fluroscene probe. So patient sample will show fluroscene while normal sample will not show fluroscene.

Transmission of prions: Normally prions can't Cross specie barrier they transmitted through different ways. Like as formite

If a person is effected with prions and he has wound in head and his comb is used by another person so prions can be transferred to other individual. Comb is Carrier of prion.

Prions are very slow acting immune system can't destroy them.

skyalpaca180

7. Write a class MetroLine in which you define a new type MetroLine (10 points) A MetroLine is defined to have the following private properties: • A String representing the colour of the line (e.g. blue, red, green, etc. No numbers. It's Montreal, not Manhattan!) • A collection of MetroStation This collection can be either a built in array, an ArrayList, or any other kind of collection you feel would satisfy the requirements of the class. The collection must be able to define an ordering from "beginning" to "end" of the MetroLine. It does not matter which part you consider the beginning and which part is the "end" as long as it is consistent. (We recommend using ArrayList but you are free to do otherwise if you feel it will be casier.) A MetroLine should have the following methods defined: • A constructor which takes nothing as input and performs any initialization necessary to maintain your collection of stations. • A method addstation which takes as input a MetroStation and adds it to the end of your collection. The method can assume the station is not already part of the collection and should return void. Note that the order the MetroStations are added is the same as the path the trains will travel on (or it could be the reverse path as well). • A method hasStation which takes as input a MetroStation and returns a boolean representing whether the metro line has a MetroStation with the same name or not. A method get LineColour which returns the colour of the line. • A method get First Stop which returns the MetroStation representing the first stop of the metro line. If there is no such station (ic, if the collection of MetroStation is empty), your method should return null. • A method get PriorStop which takes as input a MetroStation and returns the stop prior to the MetroStation passed as input. You may assume that the MetroStation passed as input is indeed in the collection of MetroStations If the current station is the first stop on the MetroLine then this method should return null. You may assume that there are no "loops" in the MetroLine That is, no station is present on the same line twice. A method getNext Stop which takes as input a MetroStation and returns the stop after the MetroStation passed as input. You may assume that the Metrostation passed as input is indeed in the collection of Metrostations. If the current station is the last stop on the MetroLine, then this method should return null. You may assume that there are no "loops" in the MetroLine That is, no station is present on the same line twice. For the above methods, you may assume that there is no aliasing issue. That is to say, you can use == to compare the references, or if you are using a type such as ArrayList to maintain your list of stations, you can use the indexOf or contains method defined on an ArrayList.

33. Base10 is the set of numbers created from the digits {0,1,2,3,4,5,6,7,8,9}. Whereas base2, which is the set of numbers created with {0,1}. We could similarly define base; as the ordered set of characters created from {X,Y,Z}. What is the following basez number, Yxz, in base ? Random graph For this section you will need to look at the classes Graph and GraphNode present in the appendix. A Graph consists of a number of nodes, each of which has connections to other nodes in the graph. You can think of nodes as a representation of a person in a social network (e.g. Facebook). The ArrayList connectedTo variable in GraphNodes is the list of friends that particular person has. For example, in the following graph, the node O is friends with node 1 and 2. On the other hand, node 2 and node 1 are not friends, hence the lack of link. 0-0 In the constructor of the Graph, the process of connecting nodes is randomized. Moreover, we will not allow a node to be connected to itself and we are going to assume that the arguments passed to the Graph constructor respect the following conditions: n > 2, and n > nbConnections. Pay close attention to the character order

HSS 1100 Lecture Notes - Lecture 10: Hospital-Acquired Infection, Sepsis, Hand Washing

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