BIOL 240 Chapter Notes - Chapter 3: Amp Deaminase, Creatine Kinase, Phosphocreatine
Document Summary
The thick filament to the m line in opposite directions. So, the myosin on the left of the m line has its myosin head on the left of the myosin molecule. The t tubules send this neurochemical stimulus to the sr and cause channels to open and an influx of calcium ions into sarcoplasm. Calcium ions bind to tnc and cause a conformational change, that causes a conformational change in tnt that changes its association with tropomyosin and exposes the myosin binding sites on actin. Myosin heads are perpendicular to the thick filament and will bind to the myosin binding sites. Lets say these are the filaments on the right, the myosin head groups will tilt 45 degrees to the left. Then atp will bind to the myosin head and cause it to dissociate from the actin filament. Whale muscles have 70% of sarcoplasmic proteins as myoglobin: creatine kinase: is needed in living animal tissue and post-mortem.
