. A child with very low blood oxygen levels was given a test foralpha thalassemia The test was a Northern blot test using astandard probe that binds to alpha globin mRNA. The resultingNorthern blot had three bands, indicating the child has threedifferent sizes of alpha globin mRNA molecules. One is normal size,one is larger than normal, and one is smaller than normal. Theparents of the patient are both from Mediterranean countries butthere is no reasonable chance that they are related.
a). Give one possible mutant genotype that the child might havethat would result in her forming three different sized alpha globinmRNA molecules, and explain how this genotype would also cause herto have low blood oxygen levels.
b). What test would you do to confirm your hypothesis?
c). Predict what results you would expect from your test if yourhypothesis is correct
. A child with very low blood oxygen levels was given a test foralpha thalassemia The test was a Northern blot test using astandard probe that binds to alpha globin mRNA. The resultingNorthern blot had three bands, indicating the child has threedifferent sizes of alpha globin mRNA molecules. One is normal size,one is larger than normal, and one is smaller than normal. Theparents of the patient are both from Mediterranean countries butthere is no reasonable chance that they are related.
a). Give one possible mutant genotype that the child might havethat would result in her forming three different sized alpha globinmRNA molecules, and explain how this genotype would also cause herto have low blood oxygen levels.
b). What test would you do to confirm your hypothesis?
c). Predict what results you would expect from your test if yourhypothesis is correct
