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20 Feb 2019

Please help me with this question. This is a question from Genetics class:

A child has been admitted to your hospital with low blood O2 levels. A test for β thalassemia (a Northern blot) was done using a standard probe for β globin mRNA. This blot gave three different bands, indicating the patient has mRNA of three different sizes: one larger than normal, one smaller than normal, and one normal. The parents of the patient are both from Mediterranean countries but there is no reasonable chance that they are related.

a. Devise a hypothesis for the genotype of the child that explains how their genotype gives β thalassemia and also three different sizes of mRNA.

b. Devise a test (or tests) that will determine if your hypothesis is correct.

c. What results would you predict your test would give if your hypothesis is correct.

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Collen Von
Collen VonLv2
23 Feb 2019

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