Question XV. The genes encoding MHC class I and classII molecules are highly polymorphic in human populations. SpecificMHC allotypes have been associated with increased susceptibility orresistance to certain viral infections. This influence of MHCmolecules on disease susceptibility can be best explained by thefact that [complete the sentence and assess each subsequentstatement (135-138) as either factually correct (= âtrueâ) orincorrect (= âfalseâ)]:
This question has confused me. The use of the word "best" seemsto imply there is one answer that is true and all others are false.Please answer this question in the context that 1. you could onlypick ONE answer as the BEST, which one you would pick and 2. if youcould answer more than one as true/best which ones would betrue
135. viral infection of DCs results in the presentation of viralpeptides by MHC molecules, which stimulates the activation of naiveT lymphocytes.
136. T cells become restricted to either MHC class I or MHC classII allotypes during their thymic development and this determineswhether they become polarized towards TH1 or TH2 responses,respectively.
137. different MHC allotypes differ in their ability to distinguishharmful compounds from harmless self antigens.
138. different MHC allotypes bind different peptides and,therefore, some allotypes can present peptides from certain virusesbetter than peptides from other viruses.
Question XV. The genes encoding MHC class I and classII molecules are highly polymorphic in human populations. SpecificMHC allotypes have been associated with increased susceptibility orresistance to certain viral infections. This influence of MHCmolecules on disease susceptibility can be best explained by thefact that [complete the sentence and assess each subsequentstatement (135-138) as either factually correct (= âtrueâ) orincorrect (= âfalseâ)]:
This question has confused me. The use of the word "best" seemsto imply there is one answer that is true and all others are false.Please answer this question in the context that 1. you could onlypick ONE answer as the BEST, which one you would pick and 2. if youcould answer more than one as true/best which ones would betrue
135. viral infection of DCs results in the presentation of viralpeptides by MHC molecules, which stimulates the activation of naiveT lymphocytes.
136. T cells become restricted to either MHC class I or MHC classII allotypes during their thymic development and this determineswhether they become polarized towards TH1 or TH2 responses,respectively.
137. different MHC allotypes differ in their ability to distinguishharmful compounds from harmless self antigens.
138. different MHC allotypes bind different peptides and,therefore, some allotypes can present peptides from certain virusesbetter than peptides from other viruses.
