1.) After receiving a vaccine containing a particlesfrom a dead virus (not able to infect cells) and an adjuvant, onewould expect a person to have increased inflammation, NK cellactivity and interferon secretion at the injection site. True orFalse, and why?
2.) If a person's Helper T cells were able to beactivated and were able to clonally expand, but were unable tosecrete cytokines, that person would be more susceptible to bothbacterial and viral infections because of decreased reponses ofCytotoxic T cells and B cells. True or False, and why?
3.)A person suffering from AIDS and a person sufferingfrom a primary immune deficiency could both have low numbers ofCD4-expressing Helper T cells, but a person suffering from anautoimmune disease probably would not. True or False, andwhy?
4.)All of the macrophages in an otherwisehealthy human are infected with a virus. The virus is able to usethe macrophage's enzymes to produce more viral particles, but itdoes not kill the macrophages. Will the macrophage be able toactivate Helper T cells, cytotoxic T cells, or both? Explain youranswer. Be sure to include a description of the interactionsbetween viral antigens, MHC molecules and TCRs found on themacrophage and/or T cells in your answer. True or False,and why?
1.) After receiving a vaccine containing a particlesfrom a dead virus (not able to infect cells) and an adjuvant, onewould expect a person to have increased inflammation, NK cellactivity and interferon secretion at the injection site. True orFalse, and why?
2.) If a person's Helper T cells were able to beactivated and were able to clonally expand, but were unable tosecrete cytokines, that person would be more susceptible to bothbacterial and viral infections because of decreased reponses ofCytotoxic T cells and B cells. True or False, and why?
3.)A person suffering from AIDS and a person sufferingfrom a primary immune deficiency could both have low numbers ofCD4-expressing Helper T cells, but a person suffering from anautoimmune disease probably would not. True or False, andwhy?
4.)All of the macrophages in an otherwisehealthy human are infected with a virus. The virus is able to usethe macrophage's enzymes to produce more viral particles, but itdoes not kill the macrophages. Will the macrophage be able toactivate Helper T cells, cytotoxic T cells, or both? Explain youranswer. Be sure to include a description of the interactionsbetween viral antigens, MHC molecules and TCRs found on themacrophage and/or T cells in your answer. True or False,and why?
Related textbook solutions
Related questions
1. A mutation in the gene encoding the integrase enzyme rendersthe protein non-functional. How would the affect the HIV infectioncycle?
| Formation of the provirus would bestopped. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Reverse transcription would nolonger be possible. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The gp120 glycoprotein would nolonger be able to bind to the CCR5 receptor. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cutting and assembling the capsid would be halted. 2. If the viral gene is AUGCCCAGG and the mRNA used to make theviral protein is UACGGGUCC, then the virus is a :
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