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A patient comes to a doctor complaining of muscle cramping. Aspart of her examination, the doctor notes that the patient has aslow pulse. Additionally, in the past year the patient has brokenher hand and her arm in seemingly minor falls. What variable do youpredict the patient is having trouble regulating? Fat K+ ATPCa2+

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Sixta Kovacek
Sixta KovacekLv2
29 Sep 2019
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Related questions

Complete Question Text:

1. A patient comes to a doctor complaining of muscle cramping.As part of her examination, the doctor notes that the patient has aslow pulse. Additionally, in the past year the patient has brokenher hand and her arm in seemingly minor falls. What variable do youpredict the patient is having trouble regulating?

Fat
K+
ATP
Ca2+

2. Allen's rule is a biological rule that states that the limbsof warm blooded animals that live in colder climates are differentthan the limbs of the same species of animals in warmer climates.In what way do you expect them to be different and why?

Shorter because a low surface area to volume ratio is best formaintaining heat
Longer because a high surface area to volume ratio is best formaintaining heat. ????
Longer because a low surface area to volume ratio is best formaintaining heat
Shorter because a high surface area to volume ratio is best formaintaining heat.

3. Pepsin is a digestive enzyme. It is made in an inactive form,pepsinogen, which is activated by the acidity of the stomach toself-cleave (cut itself) into a formed called the cleaved molecule.This cleaved molecule is active pepsin, which goes on to cleavemore pepsinogen molecules, leading to a cascade of rapid pepsinactivation (and many more active pepsin molecules). This pathway isan example of:

a feedforward regulation

a positive feedback loop

a negative feedback loop

conditioning

4. The human body's arterial blood pH is tightly maintainedaround 7.4 by buffering agents that bind hydrogen ions to stop anychange in pH. If an acid-base imbalance overcomes the buffersystem, the body changes the ventilation rate, or the rate at whichgas enters or leaves the lungs. Changing the ventilation ratechanges the concentration of CO2 in the blood, which alters the pHof the blood. In this case, the muscles that control theventilation rate are acting as the:

homeostatic challenge
sensor
effector
integrator

5. The human body's arterial blood pH is tightly maintainedaround 7.4 by buffering agents that bind hydrogen ions to stop anychange in pH. If an acid-base imbalance overcomes the buffersystem, the body changes the ventilation rate, or the rate at whichgas enters or leaves the lungs. Changing the ventilation ratechanges the concentration of CO2 in the blood, which alters the pHof the blood. In this case, pH 7.4 is the:

homeostatic challenge
sensor
effector
set point

6. What is the equivalent of the mammalian mouth and nose in therespiratory system of insects?

alveoli
spiracles
tracheoles
epithelial tissue

7. For cells to maintain an appropriate solute concentration,_____ will occur; for cells to maintain an appropriate waterconcentration, _____ will occur.

diffusion, osmosis
osmosis, diffusion
diffusion, facilitated diffusion
diffusion, active transport

8. A marine fish with a cold body temperature that matches itscold surroundings is an example of

negative feedback

regulating
conforming
homeostasis

9 Fiddler crabs are small crabs that inhabit intertidal areas.When the tide comes in, the salinity rises to 35ppt and when thetide leaves, the salinity falls to 5ppt. Fiddler crabs can maintaintheir internal salinity at 32ppt when the external environmentranges from 20-40ppt, but cannot regulate at levels higher or lowerthan this. The range of 20-40ppt is the ____________________ forthese animals.

zone of conforming
zone of stability
osmoregulator conforming capacity
positive feedback effector range

10. Imagine you are entering a darkened cavern. You are excited,but also a little nervous. Your heart rate quickens, your bloodpressure rises slightly, and your digestive system activitydecreases as blood is diverted to your muscles—all changes thatprepare you should you need to move rapidly. This type of change isan example of:

positive feedback control
negative feedback control
a failure of homeostasis
feedforward regulation

Personal Information

Name: Mrs. Paula Johnson

Age: 65 years old

Gender: Female

Description

Mrs. Paula Johnson is a 65-year-old white woman with a previous history of a sedentary lifestyle, hypertension, hypercholesterolemia, and diabetes mellitus type II. She is a heavy smoker since she was 20 years old. She was brought to the emergency room because her family found her unresponsive on the floor. She was diaphoretic. Her family thought she had her diabetes decompensated. Mrs. Johnson’s daughter indicated her mother was complaining of nausea and epigastric pain the day before. Also, her blood pressure was high.

On the physical examination we found:

Remarkable Signs on Physical Exam by Regions

Chest: Palpitation

Remarkable Signs on Physical Exam by Systems

Integumentary system: Profuse diaphoresis, coldness, and pallor

Respiratory system: Tachypnea

Cardiovascular system: Weak pulse, tachycardia, and hypotension

Nervous system: Unconsciousness. No other neurologic signs.

Lab Tests

Complete blood count (CBC)

Cardiac enzymes

Glucose level

Lipid panel

EKG

Cardiac catheterization

Diagnosis

Silent myocardial infarction

Other Diagnoses

Essential hypertension

Dyslipidemia

Diabetes mellitus

Supporting Material

Mrs. Johnson has been diagnosed with silent myocardial infarction. As we learned last module, the first step in pathophysiology is observation of noticeable changes, but what do we do when the patient does not outwardly experience symptoms? Chest pain is a scary symptom that usually alerts the physician and patient. However, if the patient or the physician is not alerted, the medical practitioner has to dig deeper to understand the cause or set of causes that contribute to the condition.

What are your initial reactions related to the case?

What is a heart attack?

Considering Mrs. Johnson’s case, why does she have an increased risk of having a heart attack?

What is tissue perfusion? Which of the patient’s conditions can alter tissue perfusion? How?

What is hypertension? How does hypertension alter tissue perfusion?

Describe pneumonia. What risk factors does the patient have for pneumonia?

Based on the following case study respond to these questions:

1. The patient in our case study, Mr. Franklin, had dizziness and was found on the floor. What traumatic brain injuries do we have to rule out?

2. How do we clinically know if the patient was having a seizure attack?

3. Is it probable that he has a new cerebrovascular accident? Explain

4. What risk factors does Mr. Franklin have of suffering from dementia in the future?

Personal Information

Name: Mr. Christopher Franklin

Age: 60 years old

Gender: Male

Description

Mr. Franklin is a 60-year-old patient with a history of a thrombotic cerebrovascular accident two years ago. After the stroke, he started with seizure attacks. He has been suffering from hypertension for the last ten years and ulcerative colitis since last year. He currently takes lisinopril, hydrochlorothiazide, aspirin, carbamazepine, and a low dose of prednisone.

Mr. Franklin has been suffering from epigastric pain, a sensation of fullness, and occasional nausea for the last six months. This time, he was brought to the ER because, while he was talking to his son, he had a dizzy spell and fell to the floor. He is conscious and is complaining of severe epigastric pain. He began with mild abdominal pain two days after he started taking a new cycle of prednisone for his colitis, around seven days ago. The pain increases when he eats or drinks something. He is also complaining of suffering from pyrosis, malaise, and dizziness, and he has noticed that his feces are dark.

The patient was a heavy alcohol drinker until he had the stroke. He is a cigarette smoker since he was 20 years old. His mother suffered from Alzheimer’s disease and died of colon cancer, and his father died of cirrhosis of the liver.

On physical examination we found:

Remarkable Signs on Physical by Regions

Abdomen: Pain on palpation on epigastric region

SOMA: Right hemiplegia and hyperreflexia

Remarkable Signs on Physical by Systems

Integumentary system: Pallor, diaphoresis, coldness

Cardiovascular system: Tachycardia. Blood pressure 70/50 mmHg. Radial pulse 110.

Digestive system: Tenderness of epigastric region. A rectal exam showed melena.

Neurologic system: The patient is conscious and well oriented to time, place, and person. Right hemiplegia and hyperreflexia.

Lab Tests

Complete blood count (CBC)

Metabolic panel

Lipid panel

Abdominal CT scan

Esophagogastroduodenoscopy

Main Diagnosis

Upper digestive bleeding due to drug-induced gastritis

Hypovolemic shock

Acute anemia

Other Diagnoses

Stabilized thrombotic cerebrovascular accident

Epilepsy

Essential hypertension

Ulcerative colitis

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