Question

Which of the following factors does NOT contribute to our inability to predict protein tertiary structure using only our knowledge of protein primary structure?

A. The large number of monomers available, as well as the relatively large size of proteins constructed with these monomers, means that almost every protein tertiary structure will be complicated.

B. We cannot reliably predict which stretches of a protein primary structure will definitively form a particular element of secondary structure.

C. There is no predictable trend as to which intermolecular forces (ionic interactions, hydrogen bonds, etc.) are more or less important in determining a protein tertiary structure.

D. All the other answer choices contribute to our inability to predict protein tertiary structure using only our knowledge of protein primary structure.