Autoimmunity may be triggered by which one of the following?
A. Impaired T-cell function
B. Non-sensitized B lymphocytes
C. Close resemblance between the foreign and self antigen.
D. Elimination of all self-reactive lymphocytes
Autoimmunity may be triggered by which one of the following?
A. | Impaired T-cell function | |
B. | Non-sensitized B lymphocytes | |
C. | Close resemblance between the foreign and self antigen. | |
D. | Elimination of all self-reactive lymphocytes |
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Which of the following statements about induction or maintenance of T cell tolerance is NOT true?
a. | Peripheral T cell tolerance to an antigen may be induced by persistent and repeated stimulation of lymphocytes by that antigen in tissues. | |
b. | Peripheral T cell tolerance results when T cells recognize antigen in the setting of an innate immune response to the antigen. | |
c. | Peripheral T cell tolerance to some antigens is induced when mature T cells recognize antigen and bind B7-1 or B7-2 via the inhibitory CTLA-4 receptor. | |
d. | Peripheral T cell tolerance results when mature naive T cells recognize antigens without adequate B7-1â or B7-2âmediated costimulation. | |
e. | Central tolerance is induced when immature developing T cells in bone marrow or thymus encounter self-antigens. |