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Industrial workers that were exposed to a strong mutagen for a limited period of time do not usually begin to develop cancers until at least 20 years after the exposure. Suggest an explanation for this long delay between exposure and cancer diagnosis. (3 points)

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Nestor RutherfordLv2

5 Feb 2019

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1. Which of the following is the PRIMARY goal of risk assessment?

A. maximize profit

B. balance risks and benefits

C. reduce liability

D. determine lethal doses

2. The probability of an adverse outcome based on the exposure and potency of a hazardous agent is known as the:

A. toxicity

B. risk

C. hazard

D. margin of safety

E. therapeutic index

3. Risk Assessment includes all the following, except:

A. risk characterization

B. exposure assessment

C. dose-response assessment

D. hazard identification

E. cost-benefit analysis

4. The process of making risk information understood by local officials, community groups and other stakeholders is known as:

A. risk management

B. risk characterization

C. risk communication

D. risk perception

E. risk estimation

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A. in vitro testing

B. structure-activity relationships

C. animal bioassays

D. epidemiologic data

E. all of the above

6. A basic premise of carcinogen risk assessment is that:

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B. chemicals that cause tumors in animals will cause tumors in humans

C. all dosing regimens are equivalent

D. all animal strains are relevant

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A. NOAEL

B. LOAEL

C. BMDL

D. none of the above

E. all of the above

8. The benchmark dose (BMD) approach is preferred over the NOAEL/LOAEL approach for all the following reasons, except:

A. the full dose-response curve is considered

B. it includes a measure of variability

C. the same benchmark response be used across studies

D. it results in lower reference values

9. A biochemical change, functional impairment, or pathologic lesion affecting an organismâs performance, and reducing its ability to respond to environmental challenges is known in risk assessment as the

A. point of departure

B. benchmark dose

C. adverse effect

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A. high concern

B. moderate concern

C. somewhat low concern

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A. arsenic

B. lead

C. methylene chloride

D. dioxin

E. formaldehyde

12. Which if the following was NOT an event in the United States that triggered widespread awareness of environmental issues in the 1960s?

A. Relocation of families from Love Canal in Niagara Falls, NY

B. Cuyahoga River catching on fire in Ohio

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D. Nationwide federal ban of smoking cigarettes in bars and restaurants

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A. A volcano

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A. Ozone

B. Carbon monoxide

C. Carbon dioxide

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A. Chlorine

B. Chloramine

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A. Point source

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