Biology 1002B Lecture Notes - Lecture 15: Histone H2B, Noncoding Dna, Chromatin

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Clicker: which of the following signals in dna is understood by the cell through protein binding to nucleic acid: polyadenylation signal is a site that cuts the mrna off so it is understood. Gets recognized by protein to get cut after it gets transcribed into mrna: operator, enhancer. Clicker: if identical twin sisters each have a son with identical twin brothers, the kids will be identical: false , gametes are different, sexual recombination. Environmental mutagens: only females: different active x in different tissues. Random x chromosome inactivation creates genetic mosaics: rainbow was a cat, and they cloned the cat and they look very different because the inactivation of x. Same genotype, different phenotype: at about 100 cells the both x chromosomes are active but then the cells undergo inactivation. Xist rna binds along the inactive x chromosome, silencing most genes: very condensed x chromosome called bar body, xist -> x inactive specific transcript, they keep the x chromosome inactive.

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