Biology 1002B Lecture 17: "Cancer"
24 Aug 2013
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Document Summary
The methylation of cytosine is one common mechanism of epigenetics. The direct modification of histones (with the acetylation or methylation of histone tails) is another mechanism by which this can occur. Chromatin remodeling is also an example of epigenetic regulation. When vertebrate females inactivate x chromosomes, a mosaic between paternal and maternal x-chromosomes is observed. When making gametes, you put sex-specific methylation tags on your dna. The sd box and the terminator sequence (in prokaryotes) are examples of sequences that are transcribed, but not translated. Enhancers and er target sequences do not fall into this category as enhancers are not even transcribed and. Er target sequences are both transcribed and translated. One notion is that chromatin which is loose and available will become more likely to be transcribed. In the chromosome with less available chromatin, it is typically inactivated almost entirely.
