SCIE 1P51 Lecture : Genes
17 Feb 2012
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Document Summary
The manipulation of a genome: to correct a disease or medical condition by the insertion, mutations, or deletion of genetic material (gene[s]) to produce a therapeutic outcome. Add markers to mutated gene (most common: green jellyfish protein, red coral fish protein) Breed mice to establish germ line patterns of inheritance of mutation. A bacteriophage, plasmid, or other agent that transfers genetic material from one cell to another. Destroys invading dna, cut dna at specific sites. Not found in humans-purified for lab use in test tube. Useful for cutting out a section of the dna containing what you want- such as a gene. Two sets of ends are "sticky" and will match. Dna from plasmid and gene can be "glued" back together.
