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Coronaviruses have been infecting humans for decades, but differ in their pathogenesis. Why do the currently circulating coronaviruses (HCoV-299, HCoV-HKU, HCoV-NL6 and HCoV-OC43) not cause acute respiratory distress syndrome?

Choose the most correct answer from below.

Select one:

a. They no longer have an animal reservoir, so are less infectious

b. They have been circulating in the population for a long time, so we have developed herd immunity

c. They infect the upper respiratory tract only

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