PAT 20A/B Study Guide - Final Guide: Latent Autoimmune Diabetes Of Adults, Diuresis, Diabetes Mellitus Type 1

• School: Ryerson University
• Department: Pathotherapeutics
• Course: PAT 20A/B
• Professor: Leo Michelis

Document Summary

Autoimmunity is considered the major factor in the. In the past known as: juvenile diabetes. Leads to a decline of glucose-stimulated insulin secretion . As beta cell mass declines, insulin secretion decreases . Late symptoms --- generally appear when 80-90% of the cells are destroyed . Commonly seen in people with lean body: also seen in normal or obese. Onset often occurs in childhood; but can also develop in adults in their late 30s and early 40s : this is referred to as lada . Lada ( latent autoimmune diabetes in adults) . Lada may account for up to 10% of adults who are classified as having type 2 diabetes. These adults are initially diagnosed as having type 2 diabetes (based on their age, risk factors strong family history or obesity) Occurs in adults, often with a slower course of onset. Risk factor= early upper respiratory infections ( greater than 5 in the first year) .