NURS 2003H Study Guide - Final Guide: Pus, Etiology, Electronvolt

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OBSTRUCTIVE PULMONARY DISEASES
Obstructive Pulmonary Diseases
collection of chronic lung diseases
omost common lung diseases
o“restrictive” coming from the body
oobstructive comes from an outside source
characterized by increased airflow resistance
oresult of airway obstruction or narrowing
Chronic Obstructive Pulmonary Disease (COPD)
oEmphysema
oChronic Bronchitis
COPD
*look at the first 4 pages of the 2017 COPD guidelines (pathophysiology)
*most common cause of COPD is smoking, air population, and fires indoors
progressive, partially reversible airflow obstruction
oincreasing frequency and severity of exacerbations
S&S
odyspnea, difficulty breathing, SOB, exercise intolerance
Pathophysiology
ochronic bronchitis
oemphysema
COPD
o*figure 31-11, 31-8
Emphysema - Pathogenesis
chronic inflammation
oairways, bronchioles, alveoli, pulmonary capillaries
classic inflammatory pathway
odestroys pulmonary tissues
neutrophils, macrophages, lymphocytes
pro-inflammatory cytokines
site of destruction determines impact
o alveoli
o bronchioles
Emphysema -Pathogenesis in Alveoli
destruction of alveolar wall
oloss of surface area for gas exchange
oloss of pulmonary capillaries due to inflammation
oloss of elastic fibers
oaltered ventilation-perfusion ratio
Emphysema – Pathogenesis in Bronchioles
Fibrosis
oresult of chronic inflammation
destruction of elastin
oloss of elastic capacity of lungs
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Document Summary

Obstructive pulmonary diseases collection of chronic lung diseases: most common lung diseases, restrictive coming from the body, obstructive comes from an outside source characterized by increased airflow resistance, result of airway obstruction or narrowing. Chronic obstructive pulmonary disease (copd: emphysema, chronic bronchitis. *look at the first 4 pages of the 2017 copd guidelines (pathophysiology) *most common cause of copd is smoking, air population, and fires indoors progressive, partially reversible airflow obstruction: increasing frequency and severity of exacerbations. S&s: dyspnea, difficulty breathing, sob, exercise intolerance. Emphysema - pathogenesis chronic inflammation: airways, bronchioles, alveoli, pulmonary capillaries classic inflammatory pathway, destroys pulmonary tissues neutrophils, macrophages, lymphocytes pro-inflammatory cytokines site of destruction determines impact, alveoli, bronchioles. Emphysema -pathogenesis in alveoli destruction of alveolar wall: loss of surface area for gas exchange, loss of pulmonary capillaries due to inflammation, loss of elastic fibers, altered ventilation-perfusion ratio.