PATH 3610 Study Guide - Final Guide: Blood Sugar, Endothelium, Fat Necrosis

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Rob Foster

Document Summary

Producion of inacive enzyme precursors that are cleaved and acivated in lumen of duodenum (prevents digesion of organs) Cachexia: weakness and wasing of body due to chronic illness. Caused by obstrucion of common bile duct by gallstones (choliliths) resuling in obstrucion of pancreaic duct. Acivaion of pancreaic enzymes in pancreaic issues autodigesion. Hemorrhage from elastase digesion of blood vessels. Must keep sugar levels within normal levels because excess glucose is toxic to endothelial cells. Muscle: transmembrane transport of glucose for energy and glycogen formaion, amino acid uptake and protein synthesis, prevents breakdown. Adipocytes: lipid synthesis and prevents breakdown, maintain energy store. Afect this whole system by changing insulin, receptors, or these pathways (all induce diabetes!) Stomach is empty, no food for hours, you"ve absorbed all the food you"ve consumed. Need coninuous supply of glucose in blood. Ater a big meal, glucose supplied by intesines. Adipocytes and muscle cells take up glucose. Causes degeneraion of islets of langerhans (endothelial cells)