BCH 3170 Study Guide - Midterm Guide: Exon Junction Complex, Dna-Binding Domain, Transcription Bubble

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Transcription is the conversion of a dna molecule (template strand) into an rna molecule. The rna molecule is identical to the coding strand (5"-3"). Most of gene expression takes place in this step. Transcriptional unit: rna polymerase binds to promoter rna synthesis stops at terminator sequence. Promoter sequence encompasses the first nucleotide transcribed into rna, the transcriptional start site or the +1 position. Messenger rna (mrna): rna that contains information for the synthesis of a sequence of amino acid that constitutes a protein. Other types of rna include trna and rrna, both involved in how information in mrna is transferred to proteins. Transcribed mrna is not modified in prokaryotes but several modifications in eukaryotes. The difference between % equilibrium and synthesis capacity reflects the stability of the different rna"s. mrna is much less stable than rrna or trna. mrna is rapidly degraded following protein synthesis. Transcription often aborts at this stage and the short chains are released.

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