BIO 1140 Study Guide - Final Guide: Telomerase, Homeostasis, Signal Peptide

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Objective 4: discuss the role of membranes, and in particular the plasma membrane, in a cell. Boundary (selective permeability) diversity in lipid and protein content-fluidity, diffusion. The plasma membrane is asymmetric due to the: di erent ratios of phospholipids on both lea ets, integral proteins, presence of glycoproteins and glycolipids, varying amount of cholesterol introduced or removed, understand and explain the uid mosaic model. Plasmodesmata: important for muscle contraction and dilation of blood vessels, identify and compare the basic signalling pathways, lipid rafts: micro-domains (accept small areas or regions) of membrane that are rich in sphingolipids and cholesterol. Events: main goal is to activate pka activity, protein kinase a phosphorylates various proteins that are involved in metabolic pathways, availability of neurotransmitters, phosphorylate transcription factor, once the g-protein is activated, the alpha subunit dissociates which activates. Arachidonic acid (eicosanoids: aids in apoptosis, plc cleaves pip2 into dag & ip3 > ip3 directed to ip3-gated ca2+ channel on er .

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